Classical Pathway Activation in Neurodegenerative Disease

Time: 2:00 pm
day: Track B - Day 1 PM

Details:

  • Activated glial cells express classical complement pathway components during neuroinflammation
  • C1Q or C3 knockout provide similar protection against neurodegeneration in Alzheimer’s disease and frontotemporal dementia mouse models
  • Elevated levels and increased activation of the classical pathway is found in the central nervous system of neurodegeneration patients

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Speakers: