Long-Term Graft Survival Achieved in NHP Recipients of Life- Sustaining, Endogenous Retrovirus-Free, Human-Compatible (Huco™) Porcine Renal Xenografts

Time: 12:30 pm
day: Day Two


  • Understand how genome-wide inactivation of porcine retroviruses greatly reduces the risk of zoonosis in xenotransplantation
  • Human immune-compatibility of retrovirus-free porcine organ donors was enhanced using multiplex, precision genome editing to produce a safe source of human-compatible (HuCo™) porcine organ donors for human transplantation
  • Demonstrating how human complement regulatory protein expressing HuCo™ donor kidneys show long-term survival in an NHP model of life-sustaining renal xenotransplantation