Panel Discussion: Uncovering the Latest Technology in Preclinical Modelling Through the Promise of Humanized Complement Models in Drug Development
- Evaluating the utility of humanized complement models for testing complement inhibitors
- Delving into their advantages for human targeted agents
- Addressing key challenges such as incomplete humanization, low human protein expression and functional assay development
- Understanding how humanized complement models can be used to inform complement inhibitor dose prediction