Jeffry B. Lawrence

Jeffry B. Lawrence

Company: Formerly at Solid Biosciences

Job title: Industry Expert

Seminars:

Panel Discussion: Defining the Therapeutic Windows of Drugs to Ensure Patient Safety Whilst Maintaining Drug Efficacy 9:50 am

Balancing the therapeutic index versus safety in targeting complement Discussing this in the context of disease versus healthy complement inhibition Reviewing the therapeutic window when you target classical, lectin or alternative pathways Discussing pharmacokinetics of targeting complement Specifying inclusion/exclusion criteria put in place specifically due to safety considerations e.g. avoiding comorbidities or infectionsRead more

day: Day One

Complement Inhibitory Drugs: Dose Selection & Schedule for Different Indications Based Upon Disease Mechanism, Pharmacokinetics & Pharmacodynamics 9:20 am

Assess how magnitude and clinical impact of complement activation in different diseases may differ significantly The optimal doses and schedules of administration of the same drug in different diseases may differ substantially Examine how the determination of optimal dosing in different diseases depends upon mechanism of complement activation and may be facilitated by pharmacokinetics and…Read more

day: Day One

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