Maximising the Therapeutic Potential of Complement Mediation Across Diverse Indications

INDUSTRY NEWS: Apellis Secures FDA Approval for EMPAVELI as a First Treatment for C3G and Primary IC-MPGN

INDUSTRY NEWS: AstraZeneca’s Gefurulimab Meets All Endpoints in Phase III PREVAIL Trial for Generalized Myasthenia Gravis

INDUSTRY NEWS: Regeneron’s Cemdi-Poze Combination Shows Near-Complete Complement Inhibition in PNH and AMD Trials

Diving Into the Complement Cascade to Explore Intervention Points, Harnessing Biomarker Strategies to Identify Optimal Patient Populations, & Exploring the Therapeutic Opportunity from Rare Disease to Inflammation to Autoimmune Disease

2025 brought significant excitement and progress to the complement-based therapeutic landscape. Leading biopharma companies like Novartis, Annexon Biosciences and Omeros, made significant clinical progress in PNH, AMD, IgAN and C3G, whilst key academics such as Michael Holers, Michael Brenner, and Brahm Segal continued to make discoveries in complement imaging, novel pathways, and new therapeutics areas such as oncology and transplantation.

The Complement-Based Drug Development Summit returned for its 9th year to unite the leading experts in complement biology and therapeutic development, from innovative biotech to impactful large pharma and academic experts. This meeting harnessed the energy and dedication deepening the understanding of the complement system to advance drug development in rare disease and beyond with patients at the forefront.

The 2025 meeting to gained insights from 20+ expert speakers covering the end-to-end complement-based drug development, from basic biology to diagnostics and clinical development.

Attendee's participated in three dedicated workshops for active discussion on key topics including the intracellular complement system, bispecific complement mediators, and innovative delivery of complement-based therapeutics to ensure delivery to the correct targets.

This comprehensive program spanned a broad spectrum of renal, ophthalmic, neurological, and haematological indications, mirroring the shift in focus of the complement field from rare orphan indications to larger patient populations.

Attendee's joined 80+ industry experts in December and accessed exclusive insights into therapeutic development across the complement field and brought actionable learnings and competitive intelligence back to their teams.

Download the 2025 Full Event Guide

Brochure - 9th Complement-Based Drug Development Summit

2025 World-Class Speaker Faculty Included:

View The 2025 Full Event Guide:

  • 20+ Industry Expert Speakers Shared Groundbreaking Research & Strategies
  • 1 Pre-Conference Workshop Day
  • 10+ Hours of Networking With Likeminded Complement Peers
Brochure - 9th Complement-Based Drug Development Summit

Companies on the 2025 Program:

annexon biosciences
Sanofi
Apellis
Argenx
complement therapeutics
Invizius Limited
Inflarx
Cleveland Clinic
University of Colorado
Moffit Cancer Centre
Sanegene Bio
Beacon Therapeutics
Northwestern University
Cascade Biotechnology
NIH
Harvard Medical School
Kriya Therapeutics
Character Biosciences

Testimonials:

alexion

“The small size of the conference allowed for meaningful connections and discussion and also provided an opportunity to clarify on some of the novel approaches.”

Executive Director, Medical & Clinical Development

Amgen

“I liked the small personable setting with a lot of valuable speakers who specialize in the field of complement.”

Senior Medical Science Liaison

Bio Cryst

“Great for all academic and industry developers having a productive discussion”

Director

Our 2025 Partners:

Machaon Diagnostics
Hycult Biotech
CompTech
National Jewish Health
Quidel Ortho
Svar Logo - Partner

Other Events in the Series: