Diving Into the Complement Cascade to Explore Intervention Points, Harnessing Biomarker Strategies to Identify Optimal Patient Populations, & Exploring the Therapeutic Opportunity from Rare Disease to Inflammation to Autoimmune Disease
2025 brought significant excitement and progress to the complement-based therapeutic landscape. Leading biopharma companies like Novartis, Annexon Biosciences and Omeros, made significant clinical progress in PNH, AMD, IgAN and C3G, whilst key academics such as Michael Holers, Michael Brenner, and Brahm Segal continued to make discoveries in complement imaging, novel pathways, and new therapeutics areas such as oncology and transplantation.
The Complement-Based Drug Development Summit returned for its 9th year to unite the leading experts in complement biology and therapeutic development, from innovative biotech to impactful large pharma and academic experts. This meeting harnessed the energy and dedication deepening the understanding of the complement system to advance drug development in rare disease and beyond with patients at the forefront.
The 2025 meeting to gained insights from 20+ expert speakers covering the end-to-end complement-based drug development, from basic biology to diagnostics and clinical development.
Attendee's participated in three dedicated workshops for active discussion on key topics including the intracellular complement system, bispecific complement mediators, and innovative delivery of complement-based therapeutics to ensure delivery to the correct targets.
This comprehensive program spanned a broad spectrum of renal, ophthalmic, neurological, and haematological indications, mirroring the shift in focus of the complement field from rare orphan indications to larger patient populations.
Attendee's joined 80+ industry experts in December and accessed exclusive insights into therapeutic development across the complement field and brought actionable learnings and competitive intelligence back to their teams.
Download the 2025 Full Event Guide
2025 World-Class Speaker Faculty Included:
Companies on the 2025 Program:
“The small size of the conference allowed for meaningful connections and discussion and also provided an opportunity to clarify on some of the novel approaches.”
– Executive Director, Medical & Clinical Development
“I liked the small personable setting with a lot of valuable speakers who specialize in the field of complement.”
– Senior Medical Science Liaison
“Great for all academic and industry developers having a productive discussion”
– Director