Complement Coagulation Crosstalk in Neutrophil Biology and Related Models
Time: 3:30 pm
day: End of Day Two
Details:
- Exploring how neutrophils regulate blood clotting and inflammation through Neutrophil Extracellular Trap (NET) formation triggered by the complement
- Using donor-derived neutrophils, advanced genetic tools and animal modeling, two receptors were identified as essential for complement-mediated NETosis
- Highlighting how NETs regulate clotting and inflammation, providing insights into their role in disease
