Michael Holers

Michael Holers

Company: University of Colorado

Job title: Professor of Medicine & Immunology

Seminars:

Panel Discussion: Uncovering the Latest Technology in Preclinical Modelling Through the Promise of Humanized Complement Models in Drug Development 9:30 am

Evaluating the utility of humanized complement models for testing complement inhibitors Delving into their advantages for human targeted agents Addressing key challenges such as incomplete humanization, low human protein expression and functional assay development Understanding how humanized complement models can be used to inform complement inhibitor dose predictionRead more

day: Conference Day Two

Chair’s Opening Remarks 8:50 am

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day: Conference Day One

New Frontiers in Complement Imaging for Accurate Assessment of Activated Proteins within the Cascade 12:00 pm

Identifying and validating immune-related blood-based biomarkers to serve as reliable read-outs for complement mediated diseases Delving into the complexities of discovering, developing, and validating biomarkers that accurately reflect the efficacy of complement-targeting drugs Focussing on generalized markers of complement activation an inflammation the retain relevancy across various conditions, moving beyond organ-specific structural biomarkersRead more

day: Conference Day One

Chair’s Closing Remarks 5:00 pm

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day: Conference Day One

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