Tuesday October 26 | 1pm - 3pm ET
Deep Dive Into the Role of Complement in Ocular Disease Manifestation and Progression
13:00 - 15:00
- Understanding the role of complement dysregulation in manifestation and progression of ocular diseases such as geographic atrophy, age-related macular degeneration, corneal inflammation, and uveitis
- Outlining current standard of care, standard lines of therapy and combinations, and how novel anti complement therapies are changing the continuum of care for ocular disease patients
- Discussing disease-specific clinical challenges, such as drug delivery into the eye
Dr. Sharma completed her PhD in stem cell biology in India. She joined Dr. Bharti’s laboratory as a postdoctoral fellow and developed protocols to manufacture iPS cell derived RPE patch from AMD patients. Recently, she was promoted to a staff scientist position within the Bharti lab at the National Eye Institute. She manages the group that has developed a macular degeneration model using iPS cell RPE and discovered potential drug targets that are currently being tested in vitro and in vivo.
Rosario Fernandez-Godino received her PhD in Genetics and Cell Biology from the University Complutense of Madrid (Spain) in 2009. She joined the Ocular Genomics Institute of Mass Eye and Ear at Harvard Medical School (Boston, USA) as a postdoctoral researcher to study the role of the complement system in macular degenerations. In 2016, she became a young faculty and in 2020 she was promoted to Assistant Professor of Ophthalmology at Harvard. Her research has focused on understanding the roles of the complement system and extracellular matrix in the RPE pathology of early-stage age-related macular degeneration (AMD) with the aim of developing efficient therapeutic strategies to treat dry AMD. Dr. Fernandez-Godino was recently recruited by Intergalactic Therapeutics as the Head of the Retina Biology Lab. At Intergalactic, she leads the pre-clinical efforts to develop non-viral gene therapy to treat retinal diseases.
National Eye Institute/NIH
Assistant Professor of Ophthalmology, Drug Discovery & Disease Biology
Harvard Medical School, Intergalactic Therapeutics