Pre-Conference Workshop Day
Deep Dive into the Role of Complement in Neurological Disease Manifestation & Progression
Tuesday September 27, 2022 | 14:00 - 16.30
Growing evidence has demonstrated a compelling role of the neuro-immune axis in CNS disease causality. This
workshop will provide an opportunity to get to grips with the role of complement dysregulation in the CNS disease
setting and to identify novel preclinical models and drug targets that can be pursued in the clinic.
This workshop will cover:
- Deciphering the role of complement dysregulation in manifestation and progression of neurological diseases
- Outlining preclinical models being used to study complement in the neurological setting
- Discussing disease-specific challenges of crossing the blood-brain barrier and complement activity in an immune privileged space
- Identifying therapeutic opportunities for neurological disease patients

Dorothy Schafer
Associate Professor of Neurobiology
UMass Chan Medical School

Cynthia A. Lemere
Associate Professor of Neurology
Brigham & Women’s Hospital &
Harvard Medical School

Andrea Tenner
Professor
University of California, Irvine